Leflunomide Api

22000 INR/Kilograms

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Product Details:

Molecular Formula C12H9F3N2O2
Taste Other
Smell Other
Shelf Life 3 Years
Storage Dry Place
HS Code 29420090
Molecular Weight 270.21 Kilograms (kg)
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Leflunomide Api Price And Quantity

Minimum Order Quantity 100kg Kilograms
Price 22000 INR/Kilograms

Leflunomide Api Product Specifications

Purity(%) 99
Usage Leflunomide is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis
Taste Other
Molecular Formula C12H9F3N2O2
HS Code 29420090
Shelf Life 3 Years
Smell Other
Storage Dry Place
CAS No 75706-12-6
Chemical Name Leflunomide
Grade Medicine Grade
Physical Form Powder
Molecular Weight 270.21 Kilograms (kg)
Type Antipyretic Analgesics and NSAIDs

Leflunomide Api Trade Information

Payment Terms Letter of Credit (L/C), Letter of Credit at Sight (Sight L/C), Cash Advance (CA), Cash in Advance (CID)
Delivery Time 2 Week
Sample Available Yes
Sample Policy Free samples are available
Packaging Details HDPE drums
Main Export Market(s) Australia, North America, South America, Eastern Europe, Western Europe, Middle East, Africa, Central America, Asia

Product Description

Leflunomide is an immunomodulatory agent used in the therapy of rheumatoid arthritis and psoriatic arthritis. Leflunomide therapy is associated with frequent elevations in serum aminotransferase levels and with rare instances of clinically apparent acute liver injury which can be severe and even fatal

Leflunomide is a derivative of isoxazole used for its immunosuppressive and anti-inflammatory properties. As a prodrug, leflunomide is converted to an active metabolite, A77 1726, which blocks dihydroorotate dehydrogenase, a key enzyme of de novo pyrimidine synthesis, thereby preventing the expansion of activated T lymphocytes. This agent also inhibits various protein tyrosine kinases, such as protein kinase C (PKC), thereby inhibiting cell proliferation. (NCI04)

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