Repaglinide APi

1100 USD ($)/Kilograms

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Product Details:

Molecular Weight 452.6 Kilograms (kg)
Storage Dry Place
Molecular Formula C27H36N2O4
Smell Other
HS Code 30044090
Taste Other
Shelf Life 3 Years
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Repaglinide APi Price And Quantity

Price 1100 USD ($)/Kilograms
Minimum Order Quantity 100kg Kilograms

Repaglinide APi Product Specifications

CAS No 135062-02-1
Physical Form Powder
Molecular Formula C27H36N2O4
Type Blood System Agents
Grade Medicine Grade
Molecular Weight 452.6 Kilograms (kg)
Usage Repaglinide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus
Storage Dry Place
Smell Other
Chemical Name Repaglinide
Shelf Life 3 Years
Purity(%) 99
Taste Other
HS Code 30044090

Repaglinide APi Trade Information

Payment Terms Cash Against Delivery (CAD), Letter of Credit (L/C), Letter of Credit at Sight (Sight L/C), Cash in Advance (CID)
Delivery Time 2 Week
Sample Policy Free samples are available
Packaging Details HDPE Drums
Main Export Market(s) Australia, South America, Eastern Europe, Western Europe, Middle East, Africa, Central America, Asia, North America

Product Description

Repaglinide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM). It belongs to the meglitinide class of short-acting insulin secretagogues, which act by binding to cells of the pancreas to stimulate insulin release. Repaglinide induces an early insulin response to meals decreasing postprandial blood glucose levels. It should only be taken with meals and meal-time doses should be skipped with any skipped meal. Approximately one month of therapy is required before a decrease in fasting blood glucose is seen. Meglitnides may have a neutral effect on weight or cause a slight increase in weight. The average weight gain caused by meglitinides appears to be lower than that caused by sulfonylureas and insulin and appears to occur only in those nave to oral antidiabetic agents. Due to their mechanism of action, meglitinides may cause hypoglycemia although the risk is thought to be lower than that of sulfonylureas since their action is dependent on the presence of glucose. In addition to reducing postprandial and fasting blood glucose, meglitnides have been shown to decrease glycosylated hemoglobin (HbA1c) levels, which are reflective of the last 8-10 weeks of glucose control. Meglitinides appear to be more effective at lowering postprandial blood glucose than metformin, sulfonylureas and thiazolidinediones. Repaglinide is extensively metabolized in the liver and excreted in bile. Repaglinide metabolites do not possess appreciable hypoglycemic activity. Approximately 90% of a single orally administered dose is eliminated in feces and 8% in urine

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